Home | Articles
Published on:December 2019
Indian Journal of Pharmaceutical Education and Research, 2020; 54(1):1-7
Review Article | doi:10.5530/ijper.54.1.1

Emerging Non-Pharmacological Therapies for Post-stroke Depression and its Future Aspects: A Review

Authors and affiliation (s):

Keerthana Chandrasekar, Nakka Gautam Sai, Princy Sabu John, Sruthi Ninan, Raja Durai, Sivasankaran Ponnusankar*

Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamil Nadu, INDIA.


Post-Stroke Depression (PSD) is a psychiatric disorder associated with stroke which has an adverse effect on the cognitive function and survival. It usually develops in 40% of the stroke survivors within 3 months. We performed a thorough literature review using PsychInfo, PubMed, Science Direct and PLOS databases for the non-pharmacological treatment of PSD. Early rehabilitation and psychological therapies are effective in treating depression in PSD while physiotherapy and music therapy improves both cognitive and movement disability. Transcranial stimulation and electroconvulsive therapy are invasive procedures used to treat cognitive impairment in PSD. Computerized therapy helps, enhance the attention, memory and executive functioning. DepReT stroke is a package which addresses patients along with their caregiver to have a better understanding of the depression. Robot assisted rehabilitation along with traditional rehabilitation is effective in treating motor function associated with PSD. Early assessment, treatment and rehabilitation are the most effective ways to prevent depression in stroke survivors and thereby improving their quality of life. Non-pharmacological treatment for post-stroke depression seem to be efficacious as antidepressants in improving depressive symptoms with minimal side effects.

Key words: Caregiver, Cognitive Impairment, Non-Pharmacological Treatment, Post- Stroke Depression, Quality of Life, Rehabilitation.



Impact Factor

IJPER - An Official Publication of Association of Pharmaceutical Teachers of India is pleased to announce continued growth in the 2019 Release of Journal Citation Reports (source: 2018 Web of Science Data).


Impact Factor® as reported in the 2018 Journal Citation Reports® (Clarivate Analytics, 2019): 0.425

User login

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.


IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs