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Published on:Apr 2012
Indian Journal of Pharmaceutical Education and Research, 2012; 46(2):174-178
Original Article | doi:NILL

In-vitro Antibacterial Screening of Selected Folklore Indian Medicinal Plants with few Clinical Pathogens

Authors and affiliation (s):

V.S. Sudhanandh1*, J.K. Arjun 2, A. K. Faisal1, M.V. Ani 2, V.S. Renjini1 and K. Narendra Babu1

1Microbiology laboratory, Chemical Sciences Division, Centre for Earth Science Studies, Akkulam, Thiruvananthapuram-31, Kerala, India

2School of Biosciences, Mahatma Gandhi University, Priyadarsini Hills, Athirampuzha, Kottayam, Kerala, India


Antibacterial activities of 7 plant extracts were evaluated against 5 bacterial strains using well diffusion assay at different concentration (10%, 20% and 30%) and the results were compared with therapeutically used antibiotics. Rapid formation of inhibition zones within 24 hours of incubation was obtained with ethanolic extracts (30%) of Justicia gendarussa against all tested strains. Ethanol extracts (30%) of the Gymnema sylvestre produces a maximum inhibition zone of 24mm against Pseudomonas aeruginosa which are known to be multi-resistant to drugs, while the standard values lies behind 17mm. Cluster analysis was applied to find out the similar groups of solvent extracts in their antibacterial action. Ethanolic plant extracts figured a separate cluster with the high antibacterial activity. Significant correlations were observed between the extract concentrations and antibacterial activity (P > 0.01).

Key words: Antibacterial activity, plant extracts, inhibition zone, cluster analysis



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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.


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