Home | Articles
Published on:October 2020
Indian Journal of Pharmaceutical Education and Research, 2020; 54(3s):s411-s422
Review Article | doi:10.5530/ijper.54.3s.139

3D-printed Drugs: A Fabrication of Pharmaceuticals towards Personalized Medicine


Authors and affiliation (s):

Muhammad Salahuddin Haris1,2,*, Nur Hakimah Mohd Azlan2, Muhammad Taher1, Shaiqah Mohd Rus2, Bappaditya Chatterjee3

1Department of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, MALAYSIA.

2Advanced Drug Delivery Lab, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, MALAYSIA.

3Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management (SPPSPTM), SVKM's NMIMS, Mumbai, Maharashtra, INDIA .

Abstract:

Background: Three-dimensional (3D) printing fabricates a structure by depositing materials layer-by-layer to form an object. Drug personalization receives attention due to problems arising from drug treatments such as undesirable side effects and ineffective drug therapy among pediatric and geriatric patients. Hypothesis: Conventional dosage form faces issues such as non-adherence to medication, ineffective treatment due to non-preferable dosage form and non-optimized drug release. Personalized 3D printing drugs offer personalized drug dosing, novel drug release profile and unique dosage form production. Results and Conclusion: Therefore, this review discussed the benefits of 3D-printed drugs and an overview of the standard 3D printer technology used in pharmaceuticals. This article aimed to review the current application of 3D-printed drugs in the personalization of drug dosing, the variation of drug release profile and fabrication of unique drug dosage form. Further research and experimentation of 3D-printed drugs are recommended as they will offer a significant aid in the customization of medicine. The potential utilization of 3D-printed drugs in optimizing effective and safe medication is undeniable. However, there are some challenges needed to be overcome, such as compatibility between chosen methods with materials used, difficulty to scale-up production, regulatory requirement as well as protection of individual rights issues.

Key words: 3D-printed drugs, Personalized dosing, 3D printer, Polypills, Patient compliance, Drug release profile.

 




 

Impact Factor

IJPER - An Official Publication of Association of Pharmaceutical Teachers of India is pleased to announce continued growth in the 2019 Release of Journal Citation Reports (source: 2018 Web of Science Data).

 

Impact Factor® as reported in the 2018 Journal Citation Reports® (Clarivate Analytics, 2019): 0.425

User login

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

DOI HISTORY

IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs