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Published on:December 2020
Indian Journal of Pharmaceutical Education and Research, 2020; 54(4):865-874
Review Article | doi:10.5530/ijper.54.4.179

Using Chloroquine and Hydroxychloroquine in the Treatment of COVID-19: Does It Make Sense?

Authors and affiliation (s):

Ronan Batista

Department of Organic Chemistry, Chemistry Institute, Federal University of Bahia, Salvador, Bahia, BRAZIL.


The severe acute respiratory syndrome caused by the new coronavirus SARS-Cov-2 (COVID-19) has quickly turned into a pandemic, infecting more than 10 million people and causing more than 500,000 deaths worldwide. The absence of an effective treatment against this disease has led several researchers to investigate the possibility of redirecting drugs already known to be effective against other diseases in the treatment of COVID-19, among them the antimalarial drugs chloroquine and hydroxychloroquine. This review aims at showing how chloroquine and hydroxychloroquine came to be considered as possible drugs in the treatment of COVID-19 and how the recent in vivo experiments described so far shed light on the adequacy of this use.

Key words: COVID-19, SARS-Cov-2, Coronavirus, Chloroquine, Hydroxychloroquine, Antiviral activity.



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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.


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