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Published on:August 2021
Indian Journal of Pharmaceutical Education and Research, 2021; 55(3):863-871
Original Article | doi:10.5530/ijper.55.3.160

Determination of the Chemical Constituent Contents and Antioxidation Properties of Asystasia Gangetica


Authors and affiliation (s):

Marjette Ylreb Ungay Barbaza1, Kathlia Aguila De Castro-Cruz1, Chieh-Lun Hsieh2, Po-Wei Tsai 3,*

1School of Chemical, Biological, and Materials Engineering, and Sciences, Mapúa University, Intramuros, Manila, Metro Manila, PHILIPPINES.

2Educational Management Major in P.E., Graduate School, Emilio Aguinaldo College, Manila, Metro Manila, PHILIPPINES.

3Department of Medical Science Industry, College of Health Sciences, Chang Jung Christian University, Tainan, TAIWAN.

Abstract:

Background: Asystasia gangetica, also referred to as Chinese Violet is an invasive weed that has been revealed to contain biologically active components and manifest pharmacological effects. Phytochemical analysis on different extracts of A. gangetica reported that the plant contains steroids, sugars, phenolics, flavonoids, saponins, tannins and amino acids, alkaloids, terpenoids, quinines and carbohydrates and bioassay techniques performed using the plant material manifested its antioxidant, anti-asthmatic and antidiabetic properties. Materials and Methods: To further understand how the existing and the potential abilities of A. gangetica possibly work, the total phenolics, total flavonoids, total condensed tannins and total polysaccharide content of different extracts of A. gangetica have been analyzed as well as its antioxidation properties using DDPH and FRAP assays. The effect of combining A. gangetica extract to the methanolic extract of Morus alba leaves on the potency of the antioxidation properties of both plant materials was also explored. Results: Evaluation of the results revealed that A. gangetica ethanol extract is the extract most abundant in polyphenol, DCM extract in flavonoids and condensed tannins, while only a few extracts had polysaccharides. Ethanol extract has the most promising DPPH free radical scavenging activity, while methanol extract was reported to have the highest Trolox equivalent. No significant synergistic effect was observed in the combination of A. gangetica and M. alba extracts. Conclusion: These findings provide information on the A. gangetica extracts as antioxidant agents and as a source of natural products. Consequently, the results provide a new direction for medical research.

Key words: Antioxidation activity, Asystasia gangetica, Condensed tannin, Flavonoids, Polyphenol.

 




 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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