Effects of Nigella sativa (Kalonji) and Honey on Lipid Profile of Hyper lipidemic Smokers

Abstract:

Background: Hyper lipidemia refers to the excess of lipids in the blood of patients. The present study was carried out to investigate the effect of Nigella sativa (kalonji) and honey as compared with Atorvastatin on the lipid profile of hyper lipidemia patients with habit of smoking. Methodology: Purposes, 60 patients (3 groups of 20) of 35-65 years were selected. These patients were treated with 1 g of Nigella sativa (kalonji) seed, one tablespoon of honey, and Atorvastatin 10 mg daily in the morning at fasting for a period of 30 days. Results: The results obtained showed that Nigella sativa (kalonji), honey as well as Atorvastatin lowered significantly the levels of total cholesterol (TC), low density lipoproteins (LDL) and triglycerides (TGs) after 30 days of treatment. On the other hand, all the treatments increased HDL levels significantly after 30 days treatments were non-significant on TC and LDL levels of smokers. But after 30 days of treatment, Atorvastatin was significantly more effective than honey and Nigella sativa (kalonji). Honey reduced TGs level of smokers significantly over Nigella sativa (kalonji) and Atorvastatin. Conclusion: It can be concluded that both Nigella sativa (kalonji) and honey were as effective as Atorvastatin or more effective in some cases in reducing TC, LDL and TGs of hyper lipidemic smokers significantly while HDL levels were increased significantly.

Key words: Alternative and Complementary Medicine, Atorvastatin, Honey, Hyper lipidemia, Smoking, Kalonji, Preventive Medicine, Smoking.