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Published on:September 2017
Indian Journal of Pharmaceutical Education and Research, 2017; 51(3s2):s359-s362
Original Article | doi:10.5530/ijper.51.3s.47

Free Radical Scavenging Capacity and Antibacterial Activity of Wild Cirsium creticum from Turkey


Authors and affiliation (s):

Temine Sabudak1, Dumrul Gulen2, H.Hulya Orak*3, Merve Ozer1, Hilmican Caliskan1, Evren Cabi4

1Department of Chemistry, Faculty of Science and Arts, Namik Kemal University, Tekirdag, TURKEY.

2Department of Medical Microbiology School of Medicine, Namik Kemal University, Tekirdag, TURKEY.

3Department of Food Technology, Vocational School of Technical Sciences, Namik Kemal Un, Tekirdag, TURKEY.

4Department of Biology, Faculty of Science and Arts, Namik Kemal University, Tekirdag, TURKEY.

Abstract:

Background: In recent years, there is increasing interest the using of herbal extracts derived from plants in medicine and as a dietary supplements. Objective: We aimed the determination of the antioxidant and antibacterial activity of Cirsium creticum (Lam) d’Urv. subsp. creticum included Asteraceae family which is wild plant species in Trakya region. Methods: Crude n-hexane, diethyl ether, ethylacetate and methanol extracts from whole plants was used the determination of antiradical and antibacterial activity in C. creticum and compared in terms of extracts efficiency. Results: EC 50 values of DPPH activity in different solvents revealed significant differences similar to TPC content. The lowest inhibitory effect was found to be Gram negative for E. coli, despite the highest inhibitory effect against Gram positive S. aureus. Conclusion: Antiradical and antimicrobial activity results presented that C. creticum, could be evaluate in food supplements and pharmaceutical industry as natural compound, and future investigations will be aimed the isolations of biologically active compounds to define individual active components.

Key words: Cirsium creticum, Antiradical activity, Antimicrobial activity, E. coli, S. aureus.

 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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