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Published on:January 2018
Indian Journal of Pharmaceutical Education and Research, 2018; 52(2):255-261
Original Article | doi:10.5530/ijper.52.2.29

Biologically Active Metal Complexes Containing Thiazole core: Synthesis and Spectral Characterization


Authors and affiliation (s):

Nagesh Gunvanthrao Yernale1,2 Bennikallu Hire Mathada Mruthyunjayaswamy1*

1Department of Studies and Research in Chemistry, Gulbarga University, Kalburagi, Karnataka, INDIA.
2Department of Chemistry, Aditya Women’s Science and Commerce Degree College, Bhalki, Karnataka, INDIA.

Abstract:

The present study deals with the synthesis of new ligand N-(4-phenylthiazol-2-yl)-2- (pyridin-2-yl-methylene) hydrazinecarboxamide and it’s Cu (II), Co (II), Ni (II) and Zn (II) complexes and study their antimicrobial activity. The newly prepared compounds are characterized by elemental analysis, FT-IR, 1H NMR, mass, UV-visible and ESR spectral techniques. The elemental analysis data and spectral study indicates octahedral geometry for Cu (II), Co (II) and Ni (II) complexes and tetrahedral geometry for Zn (II) complex. All the compounds were tested for antimicrobial activity, the Cu (II) and Co (II) complexes showed good antimicrobial activity.

Key words: Schiff base, Thiazole, Pyridine-2-carboxaldehyde, Antimicrobial.

 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

DOI HISTORY

IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs