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Published on:November 2021
Indian Journal of Pharmaceutical Education and Research, 2021; 55(4):989-995
Original Article | doi:10.5530/ijper.55.4.199

BioFibGel: A Green Nanotechnology Based Wound Dressing


Authors and affiliation (s):

Garima Shandilya1, Kirtan Tarwadi1, Sachin Chavan1,*, Jai Singh Vaghela2

1Bharati Vidhyapeeth (Deemed to be University), College of Engineering, Pune, Maharashtra, INDIA.

2Department of Pharmacy, Bhupal Nobles University, College of Pharmacy, Udaipur, Rajasthan, INDIA.

Abstract:

Aim: Wound is a fragile and complex injury which can be as simple as a minor cut to the deep lesions and traumatic gash. Depending on the patient’s internal and external conditions, wounds can progress backward or forward. Acute hemorrhage and wound infections are the main cause of loss of life in critical conditions of war field or in traumatic accidents. Innovation: BioFibGel bandage/dressing is a green nanotechnology based wound care product which is intended to be used in trauma, combat injuries (bleeding gunshot wounds) and mangling as first-line emergency tool. The dressing can absorb and retain significant amount of water without dissolving or losing their structure, stabilize blood flow and avert bleeding. Materials and Results: BioFibGel is silver nanoparticles based hydrogel sheets/ fibers made up of gelatin, glycerin and aloe vera which are considered as ideal materials for hemostasis activities and encourages cleaning and protection from reinjures or infection and speeds wound healing along with real-time monitoring of pH of wound using carbon dots fluorescence. Conclusion: This work is an attempt to devise a wound dressing that can aid in natural blood-clotting mechanism (sparing blood loss) and providing positive environment in wound healing.

Key words: Wound, Haemorrhage, Green nanotechnology, Silver nanoparticles, Wound dressing, Carbon dots.

 




 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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