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Published on:January 2022
Indian Journal of Pharmaceutical Education and Research, 2022; 56(1):302-310
Original Article | doi:10.5530/ijper.56.1.36

Sun Protection Factor Activity of Black Glutinous Rice Emulgel Extract (Oryza sativa var glutinosa)


Authors and affiliation (s):

Farhamzah1, Anggun Hari Kusumawati1, Maulana Yusuf Alkandahri1,*, Himyatul Hidayah1, Dani Sujana2, Neni Sri Gunarti1, Nia Yuniarsih1, Sukma Dewi Apriana1, Lilis Setianingsih Agustina1

1Faculty of Pharmacy, Buana Perjuangan Karawang University, Karawang, West Java, INDONESIA.

2Diploma Program of Pharmacy, Karsa Husada Garut College of Health Sciences, Garut, West Java, INDONESIA.

Abstract:

Background: Recently, emulgel has emerged as a potential hydrophobic drug delivery method. Therefore, this study aims to evaluate the phytochemical content of Oryza sativa extract and develop an emulgel formulation using Carbapol 940 as a gelling agent. Materials and Methods: The emulsion was placed in a gel basis after preparation and the formulations were evaluated for their rheology, pH, spreading coefficient, stability, and sun protection factor. Then, phytochemical analysis of O. sativa extract was used to determine the presence of alkaloids, flavonoids, polyphenols, quinones, monoterpenoids, and sesquiterpenoids, as well as triterpenoids and steroids. Results: The entire formulations of O. sativa emulgel extract filled the emulgel formulation criteria. Furthermore, O. sativa emulgel protects against UV radiation, as indicated by the SPF value in each formulation, which increases as the dose of O. sativa extract increases. Based on the results, formulations 2 and 3 have an SPF of 5.71±0.063 and 16.07±0.072, respectively. These suggest that they both fill the Indonesian National Standard, which requires a sunscreen preparation with a minimum of four protection. Conclusion: Consequently, O. sativa emulgel extract can serve as a novel sunscreen agent against UV radiation. However, further study is required to ascertain the mechanism of action of the active chemicals found in O. sativa that function as an antioxidant and give protection against UV radiation.

Key words: Oryza sativa, Emulgel, Sun Protection Factor, Ultraviolet, Phytochemical compounds.

 




 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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