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Published on:January 2023
Indian Journal of Pharmaceutical Education and Research, 2023; 57(1):125-133
Original Article | doi:10.5530/001954642109

Selected Essential Oils as Natural Ingredients in Cosmetic Emulsions: Development, Stability Testing and Antimicrobial Activity


Authors and affiliation (s):

Rezarta Shkreli1,*, Rihana Terziu2, Lorena Memushaj1, Klodiola Dhamo3, Ledjan Malaj4

1Department of Pharmacy, Faculty of Medical Sciences, Aldent University, Tirana, ALBANIA.

2Ashmole Academy, Cecil Rd, London N14 5RJ, UNITED KINGDOM

3Department of Laboratory Technician and Imaging, Faculty of Technical Medical Sciences, Aldent, University, Tirana, ALBANIA.

4Department of Pharmacy, Faculty of Medicine, University of Medicine, Tirana, ALBANIA.

Abstract:

Background: Essential oils are currently the subject of intensive scientific study, and their potential as active medicinal compounds or natural preservatives has attracted the attention of the cosmetic and pharmaceutical industries. Objectives: The objectives of the present study were: to develop a cosmetic emulsion based on different concentrations of synthetic preservative and essential oils, applied as natural preservatives; to evaluate and subsequently compare their stability and antimicrobial activity. Materials and Methods: Various samples were prepared using different concentrations of methylparaben, and essential oils as well. The fresh samples were evaluated immediately after preparation related to organoleptic and physicochemical testing. The behavior of the samples related to light tests, accelerated tests, and microbiological stability tests as well were performed for four weeks of storage. Results: During the accelerated stability test, formulations loaded with 2% essential oils were not stable as was noted a variation in the color and liquefaction in the second week of storage at 40°C; their rheological behavior showed a significant decrease in the viscosity, varying from 4890±34.7 to 3720±37.9. For all the samples, the pH levels were within the physiological skin pH range, it varied from 6.01±0.33 to 6.92±0.19. The self-preserving activity of all the cosmetic emulsions was satisfactory. Conclusion: Cosmetic emulsions loaded with essential oils, in the concentration of 1% showed promising stability, physico-chemical characteristics, and selfpreserving properties, in different storage conditions. The formulations loaded with essential oils provide a novel alternative for the preservation of “paraben-free” cosmetic products.

Keywords: Cosmetic emulsion, Essential oils, Methylparaben, Formulation, Stability testing, Self-preserving activity.

 




 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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