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Published on:November 2019
Indian Journal of Pharmaceutical Education and Research, 2019; 53(4s):s678-s683
Original Article | doi:10.5530/ijper.53.4s.164

Cassia auriculata L.: An Ethno Medical Approach in Exploring Anti-solar Efficacy


Authors and affiliation (s):

Krantisinha Hanumant Randive1,*, Ravindra Durdundayya Hiremath1, Amolkumar Ashok Kempwade2, Anagha Ashok Patil2

1Department of Pharmaceutical Chemistry, KLES’s College of Pharmacy, Nipani, Karnataka, INDIA.

2Department of Pharmaceutics, KLES’s College of Pharmacy, Nipani, Karnataka, INDIA.

Abstract:

Objectives: The present study deals with an in-vitro screening for the anti-solar potential of aqueous and ethanolic extracts of Cassia auriculata using the UV method. Methods: Aqueous and ethanolic extracts were prepared. Thus, prepared extracts were subjected to phytochemical investigation and evaluated for antioxidant effect using DPPH and antisolar efficacy. Concentrations ranging from 7.8 to 1000 μg/mL (serial dilution) were used for the determination of radical scavenging effect and concentration of 2 mg/mL was used for screening of anti-solar potential using Shimadzu UV-1700 double beam UV-Visible spectrophotometer. Readings were recorded in triplicate and graphs were extrapolated. Results: Extracts revealed the presence of important phytoconstituents such as phenols, triterpenoids, flavonoids, tannins, saponins, phytosterols, alkaloids and glycosides. Further, it was observed that Cassia auriculata possesses remarkable antioxidant activity. Significant results of the anti-solar screening study confirm its use as a natural sunscreen. It showed a protective effect against carcinogenic UV radiation. Ethanolic extract was found to be more effective in comparison with aqueous extract. Conclusion: From the data, it can be concluded that aqueous and ethanolic extracts showed promising antioxidant and anti-solar activity which could be considered as a rational alternative to chemically prepared synthetic sunscreen formulations available in the market.

Key words: Anti-solar, Carcinogenic, Cassia auriculata Linn, DPPH, SPF, UV.

 

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IJPER - An Official Publication of Association of Pharmaceutical Teachers of India is pleased to announce continued growth in the 2019 Release of Journal Citation Reports (source: 2018 Web of Science Data).

 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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