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Published on:March 2017
Indian Journal of Pharmaceutical Education and Research, 2017; 51(2):329-336
Original Article | doi:10.5530/ijper.51.2.39

GC-MS Analysis and Antibacterial Activity of Aerial Parts of Quisqualis indica Plant Extracts


Authors and affiliation (s):

Akriti Agarwal, Rajmani Prajapati, Sayed Kalve Raza, Lalitesh Kumar Thakur*

Institute of Pesticide Formulation Technology Sector-20, Udyog Vihar, Gurgaon-122 016, Haryana, INDIA.

Abstract:

Background: Bacteria is an important group of human pathogens that causes various types of diseases. Plants are the traditional sources for many chemicals used as pharmaceutical biochemicals, fragrances, food colors and flavors in different countries especially in India. Quisqualis indica Linn. belongs to a family Combretaceae which is commonly known as Rangoon creeper has great medicinal values. Objective: To analyze the chemical constituents present in different solvent extracts of Q. indica using gas chromatography-mass spectroscopy (GC-MS) and evaluation of their antibacterial activities against human pathogens. Method: The dried aerial part of plant was extracted using three solvents like methanol, ethyl acetate and hexane at room temperature for 6 hours separately and antibacterial activity was carried out by broth dilution method. Results: 15, 12 and 18 compounds were confirmed by GC-MS qualitatively in methanol, ethylacetate and hexane extracts respectively. All extracts showed significant activity against four bacteria: Escherichia coli, Klebsiella pnemoniae, Staphylococcus aureus and Staphylococcus pneumonia which were comparable with ampicillin drug taken as positive control. Conclusion: The antibacterial result indicates that the aerial parts of plant have antibacterial activities due to presence of various phytochemical constituents. All the major components confirmed by GC-MS from different extract are biologically active molecule which indicates that the plant might have some medicinal properties.

Key words: Antibacterial activity, GC-MS analysis, Phytochemicals constituents, Quisqualis indica.

 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs