Home | Articles
Published on:December 2017
Indian Journal of Pharmaceutical Education and Research, 2017; 51(4S):s631-S636
Original Article | doi:10.5530/ijper.51.4s.92

The Optimum Extraction Process for Radix glycyrrhizae and Angelica dahurica (Fisch.) Benth.et Hook with Orthogonal Design


Authors and affiliation (s):

Hong Duan*, Ke Feng Zhai*, Wen Gen Cao, Gui Zhen Gao, Ling Ling Shan, Liang Zhao

Engineering Research Center of Natural Medicine and Functional Food, Institute of Pharmaceutical Biotechnology, School of Biological and Food Engineering, Engineering Research Center of Special Farm Seed Production, Suzhou University, 49, Bianhe Road, Suzhou, CHINA.

Abstract:

Background: To develop the optimal extractive technique of the Radix glycyrrhizae and Angelica dahurica (Fisch.) Benth.et Hook in the Fengshiding dropping pill. Methods: Single factor experiments were carried out on the effect of water-ethanol extraction by the multiple guidelines grading of the dried extract quantity, the contents of liquiritin and imperatorin. Furthermore, orthogonal experimental design was used for the optimization of cross-functional process. The dried extract quantity and the contents of liquiritin and imperatorin were used as targets. The interaction among solid-liquid ratio, ethanol concentration, extraction time and extraction times was investigated by the analysis of variance. Data processing was carried out with the multiple guidelines grading method for optimizing the extraction condition. Results: The optimal extracting condition was founded to be successively 3 decoctions with 12 times of 75% alcohol for 1 h. Conclusion: The optimal process is stable and feasible.

Key words: Radix glycyrrhizae, Angelica dahurica (Fisch.) Benth.et Hook, Liquiritin, Imperatorin, Orthogonal test.

 

Articles in PDF, ePUB and Full text are attached to this page. In order to download, print or access these formats you must be logged in.
CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
1 + 3 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.




 

User login

CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
1 + 0 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

DOI HISTORY

IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs