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Published on:April 2019
Indian Journal of Pharmaceutical Education and Research, 2019; 53(2s):s1-s17
Review Article | doi:10.5530/ijper.53.2s.44

Recent Developments on Pharmacological Potential of 1,3,4-Oxadiazole Scaffold


Authors and affiliation (s):

Bhutani Rubina1,*, Pathak Dharam P1, Kapoor Garima1, Kant Ravi1, Dutta Manni2

1Department of Pharmaceutical Chemistry, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, INDIA.

2School of Medical and Allied Sciences, GD Goenka University, Gurgaon, Haryana, INDIA.

Abstract:

Heterocyclic compounds represent the important structural key in pharmaceutical medicinal chemistry. In literature, five-membered heterocycles are reported to be a core moiety of various pharmaceutical drugs. 1,3,4-oxadiazole scaffold, among various five-membered heterocycles is an important molecule which attracts various medicinal chemist to develop a novel biologically active molecule. 1,3,4-Oxadiazole is found to bear important pharmacological activities such as anti-diabetic, antimicrobial, anti-cancer, anticonvulsant, antioxidant, anti-Alzheimer’s, anti-inflammatory, antiviral, cardiovascular, anti-tuberculosis, anti-pyretic, insecticidal. This review compiles the biological updates on various compounds containing 1,3,4-oxadiazole as a core moiety from the recent years.

Key words: Anti-diabetic, Anti-cancer, Heterocycle, Oxadiazole, Pharmacological activity.

 

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The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

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